Endocrine Abstracts

Introduction: Testosterone treatment in female-to-male transsexuals has been associated with worsened cardiovascular risk factors, acne, male-pattern baldness and more rarely with the onset of hypertension. Another frequent side effect of the treatment is aggression proneness -but rarely actual aggression- and increased libido.Case report: We present the case of a 17-year old transsexual patient referred for initiation of testosterone treatment. A low in...

Objectives: Eversense XL is a fully implantable sensor for continuous glucose monitoring (CGM) that lasts for up to 180 days. Our objective was to perform a survey on user acceptance and satisfaction among our type 1 diabetic patients who had been using the Eversense XL CGM for at least 3 months.Methods: A questionnaire was devised in which the patients were asked about their experience with the Eversense XL CGM, including:-Compari...

Introduction: Recurrences of differenciated thyroid carcinoma are occasionally hard to locate; rhTSH-stimulated FDG PET-CT may offer a higher sensitivity, particularly when thyroglobulin in high, but its utility has not been clearly established. Methods: Review of the patient’s clinical record Results: A 61 years old woman noticed a right anterior neck lump when she was 47; FNAC was suggestive of a solid papillary thyroid carc...

A 56-year-old Swedish male was diagnosed with hypertension, initially attributed to continued use of NSAIDs. These were withdrawn and treatment with 80 mg valsartan was started, but BP remained uncontrolled. A fixed combination (valsartan/hydrochlorothiazide, 80/12.5 mg) was introduced, but blood pressure remained high and hypokalemia (K+3.3 mEq/l) developed. The patient was referred to our Endocrinology Clinic for study. Treatment was switched to manidipine 10 mg/1...

Introduction and objectives: A possible increase in blood pressure (BP) and other cardiovascular risk factors has been associated with testosterone treatment (TT) in female-to-male transsexuals (FMT). Nonetheless, the available evidence does not support an increase in CV morbidity or mortality. We set out to analyze the impact of TT on BP and lipid profile in a cohort of FMT patients.Methodology: Retrospective observational study with no control group in...

Introduction: Interferon treatment for hepatitis C has been associated with Graves’-like thyroiditis, developing in rare instances severe ophthalmopathy. The usual management is interferon withdrawal and high-dose corticosteroids, but it may interfere with the resolution of hepatitis. Hereby we report a case successfully treated with radiotherapy, which in our knowledge has never been previously reported.Case report: A 52-year-old woman was diagnose...

Aim: Description of a series of children and adolescents with Primary Aldosteronism (PA) diagnosed and treated in our Outpatient Hypertension Clinic from 1994 to 2018.Methods: Review of the clinical records and of the relevant literature. Values are given as mean +s.d.Results: 16 of a total of 49 patients younger than 20 years of age referred to our Hypertension Clinic from 1994 to 2018 were diagnosed of PA (33%), while 27 (55%) we...

Aim: Comparing the effect of Faster Aspart insulin (Fiasp®) with previous insulin analogues (aspart, lispro) in type I diabetic patients with sensor-augmented pump therapy.Methods: Patients with Minimed Paradigm® insulin pumps, Enlite® sensors and Guardian® software (able to automatically stop the pump infusion to prevent hypoglycemia) were switched from previous insulin to Faster Aspart. Da...

Introduction/Aim: Transgender people often worry about side effects of their hormonal therapy, including breast cancer, which is an exceedingly rare occurrence. Hereby we present the case of a patient with an uncommon metadiabetic complication that can be easily confused with breast cancer, with the aim of raising awareness on this condition.Material and Methods: Review of the Clinical Record of the patient and of the relevant literature.<p class="ab...

Aim: To establish the effect of a supplement containing 250 mg red yeast rice extract, 525 mg berberine and 50 mg coenzyme Q10 on insulin sensitivity in patients with hypercholesterolemia and prediabetes.Methods: For this open, uncontrolled study, patients of age 30–75 years, with hypercholesterolemia (LDL cholesterol >130 mg/dl and triglycerides <300 mg/dl), and prediabetes without overt cardiovascular disease, untreated in the previous 6 m...